Vetality Advotect II contains imidacloprid, and pyriproxyfen – the active ingredients found in Advantage II*. Vetality Advotect II offers vet quality protection but COSTS LESS than the national brand. These broad-spectrum topicals KILL fleas and breaks the flea life cycle preventing reinfestation! KILLS fleas and breaks the flea life cycle preventing reinfestation|Offers vet quality protection