Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.
Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.
S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.
Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protect hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.
For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication may be disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach. Denosyl 9- mg tablets are ideal for cats because of
PHS - Pet Health Solutions
Information and Policies
- Processing time may be up to 3-5 business days due to high demands.
- We restrict the resale of any Pet Health Solutions products on AMAZON, EBAY, or any third-party website.
- Once an order is processed we CANNOT change addresses or make item adjustments.
- Free Shipping on orders over $500 in the continental USA and $10 for shipping otherwise. Orders ship from Union City, CA.
- Certain shipments may require extra shipping costs due to weight, dimensions or refrigeration. If this is required, your order will be held until we can advise you of extra charges.
- We may require your first order to be paid via wire or PayPal if the order value is high enough.
- Please note: pet food does not ship free and is based on weight and zip code.
- International shipping starts at $40.00 (you will be notified if any additional shipping is required). Shipping promos are not applicable to International shipments (WE DO NOT SHIP AZODYL OUTSIDE OF THE U.S.)
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- Returns are accepted within 30 days of delivery for unopened, unused items. Restocking fees up to 25% may apply. Please return packages in a manner that can be tracked. Returns may be made with a carrier of the customer's choice. Please contact us for a return authorization before returning any items.
| Body Weight |
Total Daily Administration & Tablet Size |
| Up to 12 pounds (5.5 kg) |
One tablet of 90 mg |
| 13 to 34 pounds (6-15.5 kg) |
One tablet of 225mg |
| 35 to 65 pounds (16 to 29.5 kg) |
One tablet of 425 mg |
| 66 to 120 pounds (30 to 54.5 kg) |
Two tablets of 425 mg |
| Over 120 pounds (54.5 kg +) |
Three tablets of 425 mg |
The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.
Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
What does the liver do? The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.
Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.
